First at all, please note that VTune Performance Analyzer can support MPI and OpenMP application, but profiling data is only from single node (unless the user installed VTune Analzyer on other nodes and ready to do sampling data collection at same time).
If the user works on multi-core platform, MPI application can work on multi-core platform to simulate works on the cluster. Absolutely VTune Analyzer can collect all native profiling data although it indicates all works on the cluster.
For example, (I assumed there are 4 core in user's system)
Sampling data collection -
vtl activity -c sampling -app "/bin/mpirun, -np 4 mpi_app" run
Call graph data collection -
vtl activity -c callgraph -app "/bin/mpirun, -np 4 mpi_app" -moi mpi_app run
The user can do similar things on vtlec when you create a new activity, I think.