Depends on which 7th gen NUC. I have a NUC7i7DNHE, and have an m.2 and 2.5" in it. You install the os on the m.2 and use the 2.5" as you want. You have to get the "tall" version of the nuic so you can have the 2.5" bay.
"W10 2004, W10 May 2020, W10 20H1, W10 19041.* - A rose, by any other name, still smells. "