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Hi,
For the last month or so I've been getting an error in Device Manager/Universal Serial Bus USB Hub - Unknown USB Device (Device Descriptor Request Failed) - properties reveals:
'Windows has stopped this device because it has reported problems. (Code 43). A request for the USB device descriptor failed'.
My system is a NUC5i7RYH kit. I have the latest BIOS, and all drivers are up to date.
I have a Microsoft Wireless Comfort 5000 keyboard and Mouse connected to the wireless receiver which is in NUC front USB3 port.
I have two NexStar AC powered USB3 7x ports Hubs connected to NUC rear USB3 ports:
In NexStar Hub 1, I have attached:
1x AC powered Nexstar Dual HDD Dock,
1x external, Hub powered DVDRW.
In NexStar Hub 2, I have attached:
1x Brother J430W MFC, and
1x Epson R310 printer.
Whenever I use the NexStar HDD dock, I get severe mouse lag (whether being used or not). When the dock is turned off, there is no lag.
My question then is, how do I fix the Code 43 problem, as above? I assume that once that is fixed, I should not suffer the lag.
- Tags:
- Devices

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Hi DacorDave,
According to your description it seems to be a compatibility issue. I suggest you to verify if you are using the latest drivers for the
Microsoft Wireless Comfort 5000 keyboard and Mouse, select Windows® 10, 64bit
https://www.microsoft.com/hardware/en-us/d/wireless-comfort-desktop-5000 Software Downloads: Wireless Comfort Desktop 5000
NexStar Hard Drive Dock documentation talks about compatibility with Windows® XP, Vista , 7 and 8. It is necessary to confirm with the manufacturer if there is any diver available for Windows® 10.
http://www.vantecusa.com/en/product/view_detail/295 Vantec – Vantec NexStar Hard Drive Dock-NST-100SU- 2.5"/3.5" SATA to USB 2.0 and eSATA Hard Drive Dock
I suggest you to narrow down the issue. Unplug all USB devices from the NUC; then, plug the keyboard and mouse to the NUC, install the latest Microsoft® driver and check if you are getting any error message in device manager. Make sure you already have the BIOS version 0354 and latest Chipset, Me and USB3.0 drivers.
https://downloadcenter.intel.com/product/87570/Intel-NUC-Kit-NUC5i7RYH Drivers & Software
Then, plug one by one USB devices to the NUC and check if it is recognized properly by the NUC. If not, check if USB device manufacturer has a newer driver or firmware.
Regards,
Miguel C
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Hi DacorDave,
According to your description it seems to be a compatibility issue. I suggest you to verify if you are using the latest drivers for the
Microsoft Wireless Comfort 5000 keyboard and Mouse, select Windows® 10, 64bit
https://www.microsoft.com/hardware/en-us/d/wireless-comfort-desktop-5000 Software Downloads: Wireless Comfort Desktop 5000
NexStar Hard Drive Dock documentation talks about compatibility with Windows® XP, Vista , 7 and 8. It is necessary to confirm with the manufacturer if there is any diver available for Windows® 10.
http://www.vantecusa.com/en/product/view_detail/295 Vantec – Vantec NexStar Hard Drive Dock-NST-100SU- 2.5"/3.5" SATA to USB 2.0 and eSATA Hard Drive Dock
I suggest you to narrow down the issue. Unplug all USB devices from the NUC; then, plug the keyboard and mouse to the NUC, install the latest Microsoft® driver and check if you are getting any error message in device manager. Make sure you already have the BIOS version 0354 and latest Chipset, Me and USB3.0 drivers.
https://downloadcenter.intel.com/product/87570/Intel-NUC-Kit-NUC5i7RYH Drivers & Software
Then, plug one by one USB devices to the NUC and check if it is recognized properly by the NUC. If not, check if USB device manufacturer has a newer driver or firmware.
Regards,
Miguel C
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Well, if you're getting unknown USB device (device descriptor request failed) error then I recommend you to Change the USB Selective Suspend Settings by following these steps:
- In the Power Options click the Show additional plans.
- Then select Change settings that are currently unavailable > High performance > Change plan settings > Change advanced power settings.
- After that locate USB settings and expand it.
- Expand the USB selective suspend setting. Disable both On battery and Plugged in settings.
- Now, click an Apply button and restart the system.
After using this method, you must resolve Device Descriptor Request Failed error for Windows 10.

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