Quartus 20.1, Win 10, on high DPI displays.
It happens very often recently. After resuming from screen lock, the font from most of the Quartus UI panels (except the message panel), and all newly opened windows like Timing Analyzer, become extremely small and very hard to see.
Could you provide the snapshot of Quartus UI after you unlock the screen? I would say this issue could be independent I cant reproduce it. For testing purpose, could you try to use external monitor and let me know if the issue behave the same.