You can check all available signal tap tcl scripting by opens the Intel Quartus Prime Command-Line and Tcl API help
browser by insert command: quartus_sh --qhelp
If not found, it most likely not available. You might need to manually add/remove the signals tapped in the .stp file directly.
You need to run quartus_sh --qhelp from the command prompt.
In the command prompt, go to where the quartus_sh.exe file directory located e.g. C:\intelFPGA\19.1\quartus\bin64.
Then, run quartus_sh --qhelp and GUI window will pop up showing the detailed listing of all command-line executables and Tcl commands including usage examples.
Do you mean to run a specific instance? If so, yes.
run -instance <instance> -signal_set signal_set_1 -trigger trigger_1 -data_log log_1 -timeout 5
Just specify the <instance> that you want to run in your tcl command.