We've got this issue with two systems at the moment, one using two monitors and one using three monitors with a hp universal dock.
One system uses Intel HD Graphics, the other Intel and Nvidia.
So far I've not been able to find a solution, updating all the latest drivers does not help, updating to windows 10 1809 does not help either. We've also tried changing the DPI and intel scaling options, this does not help and makes the problem worse in that it occurs more often.
Only restarting the system seems to resolve the issue at this time. F11 or CTRL+SHIFT+WIN+B do not.
I'm at a loss. Any help would be greatly appreciated.