VS: Unable to Start program / The object invoked has disconnected from its clients.

[andrew_4619]

In Visual Studio 2013 (a fresh install) with 17 Update 2, I am getting the VS error when trying to start debug with F5 "Unable to Start program " prog_path_name "The object invoked has disconnected from its clients."

This occurs when I stop debugging from the menu rather than going for a normal program termination from within the application. VS needs to be closed and restarted to be able to run under debug. Any ideas anyone? 

[Steve_Lionel]

A Google search on the error message (one of the first things I usually try when I am unfamiliar with an error) brings up a lot of hits. This one in particular seems most relevant. Also this.