I've had these same errors popup every now and then and in every case they had to do with either the installation of a new Altera version or the installation of some other conflicting hardware that modifies the PATH variable or other environment settings.
Once I had to do a system restore to an earlier date to get rid of this but the last one was a bit easier and it was because I had SOPC paths pointing to multiple versions of SOPC directories from earlier installation.
Go through the long command line that ptf is trying to execute and see if you have incorrect paths there, that should help to find the problem.
